Serious Side effects of Cizumab

• Hypertension Cizumab can cause the blood pressure to rise and this could effect the brain. Blood pressure should be regularly monitored while on Cizumab and after stopping treatment.
• GI perforation A hole that develops in the stomach or intestine. Symptoms include pain in the abdomen, nausea, vomiting, constipation, or fever.
• Fistula This is an abnormal passage in the body. It could be fatal.
• Wounds that don't heal Cizumab should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed. This is because when a cut would be made during surgery may heal slowly or not heal at all due to the drug
• Bleeding Vomiting or coughing up blood or bleeding in the stomach, brain, or spinal cord; nosebleeds; and vaginal bleeding may happen with Cizumab. If there is serious bleeding the healthcare provider should be immediately informed.
• Infusion-related reactions Though these are rare, during infusion the patient should be carefully monitored incase they show severe infusion related reactions like hypertension leading to stroke, difficulty in breathing, allergic reaction, chest pain tremors, headache, excessive sweating.
• Kidney problems These may be caused by too much protein in the urine and can sometimes be fatal.
• Severe stroke or heart problems The drug can cause blood clots,stroke, heart attack, chest pain, and may weaken the heart to pump blood (congestive heart failure). This could be fatal.
• Nervous system and vision problems The drug can cause headache, seizure, hypertension, confusion, and blindness